Nature abhors a vacuum

They say Nature abhors a vacuum - and also that the Entropy is constantly increasing (wasn't this the reason Boltzmann took his life - the true reason, not his bipolar? I can't remember)
So anyway, Nature abhors a vacuum - that means, no empty spaces.
What is my soul filled with then?
Come on, Boltzmann - from your grave, I dare you, answer me. Did you die for nothing?!